Share Articles：Delivery of therapeutic carbon monoxide by gas-entrapping materials

Carbon monoxide (CO) has long been considered a toxic gas but is now a recognized bioactive gasotransmitter with potent immunomodulatory effects.

Share Articles：FOXP3 exon 2 controls Treg stability and autoimmunity

Differing from the mouse Foxp3 gene that encodes only one protein product, human FOXP3 encodes two major isoforms through alternative splicing—a longer isoform (FOXP3 FL) containing all the coding exons and a shorter isoform lacking the amino acids encoded by exon 2 (FOXP3 ΔE2). The two isoforms are naturally expressed in humans, yet their differences in controlling regulatory T cell phenotype and functionality remain unclear. In this study, we show that patients expressing only the shorter is

Share Articles：Induction of mouse totipotent stem cells by a defined chemical cocktail

In mice, only the zygotes and blastomeres from 2-cell embryos are authentic totipotent stem cells (TotiSCs), capable of producing all the differentiated cells in both embryonic and extraembryonic tissues and forming an entire organism1. However, it remains challenging whether and how TotiSCs, representing the very beginning of a life, can be established in vitro in the absence of germline cells. Here, we demonstrate induction and long-term maintenance of TotiSCs from mouse pluripotent stem cells

Summer School info: Mathematical Methods in Computational Neuroscience

Time: 20th July - 5th August, 2022 Place: Fred Kavli Science Center, Eresfjord, Norway Organizers: Yasser Roudi, Ivan Davidovich and Benjamin Dunn, Chewy (Chief Security Officer) NRSN offers an annual summer school that provides PhD students with theoretical and practical research training in current forefront areas of neuroscience.

Professor Yu Jihong was elected as a foreign members of the Royal Swedish Academy of Sciences

At the General Meeting on 8 September, the Royal Swedish Academy of Sciences released a list of new foreign members. Professor Yu Jihong of Jilin University was elected as a foreign member to the Class for chemistry of the Royal Swedish Academy of Sciences.